Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen
Category
Published on CMKC
Abstract
Hydrogen bond donating cosolvents have been shown to significantly reduce the solubility of acetaminophen (AAP) in ionic liquids containing the acetate anion. Reduced solubility arises from competition for solvation by the acetate anion and can be used for the design of advanced separation techniques, illustrated by the crystallization of AAP.
Journal
Chemical Communications. Volume 51, 2015, 4294-4297
DOI
10.1039/c5cc00198f
Type of publication
Peer-reviewed journal
Affiliations
- Massachusetts Institute of Technology (MIT) (MIT)
- University of Alabama
Article Classification
Research Article
Classification Areas
- API