Over the last ten years, the path to effective development of PAT has evolved, driven by the advent of continuous manufacturing. The development and deployment of PAT used for pharmaceutical manufacturing has arrived at a point where application development has been miniaturized and streamlined. The availability of fast scanning instruments using fiber optic probes, integrated into processing equipment is now a standard approach for continuous systems, and the same approach can be used for traditional batch manufacturing. The development of devices that can simulate the environment of a fiber optic probe in production equipment, using a small amount of material, in a laboratory environment has enabled the development of working models for the spectrometer using the minimum amount of material, separate from the large-scale manufacturing equipment. This capability has reduced the complexity and cost of developing PAT applications for a production environment.

• Not available

• PAT
• Oral solid dose

1. Industry 4.0
2. NIR & Raman
3. oral solid dose
4. Other
5. pat
6. sensors & computerized systems
7. simulator