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1. The Continuous-Flow Synthesis of Ibuprofen

   out of 5 stars 

   Contributor(s):: Bogdan, Andrew R., Poe, Sarah L, Kubis, Daniel C., Broadwater, Steven J., McQuade, D. Tyler

   Let relief flow forth! A three-step, continuous-flow synthesis of ibuprofen was accomplished using a simplified microreactor. By designing a synthesis in which excess reagents and byproducts are compatible with downstream reactions, no intermediate purification or isolation steps are required.

2. Continuous Synthesis of Carbamates from CO2 and Amines

   out of 5 stars 

   Contributor(s):: Stagel, Kristof, Bica-Schröder, Katharina, Lelo Laura

   We present a novel approach for the continuous preparation of carbamates. The simple yet fast synthetic route relies on directly utilizing carbon dioxide and, in contrast with the literature-known methods, only employs 1,8-diazabicyclo[5.4.0]undec-7-ene as an additive. The applicable amines’...