Advanced Manufacturing technologies (AMTs) in the pharmaceutical industry have increasingly gained attention in the last decade. Amongst the AMTs, continuous manufacturing (CM) has had the most prominent impact so far. International efforts to define manufacturing approaches, terms, regulatory expectations in a harmonised manner have been made. In many cases, manufacturers have benefited due to early adoption of CM. As the interest grows in the areas of API and drug product as well as biologics, it is important to understand the barriers and challenges for a broader worldwide adoption. USP has been working in different ways to lower some of these barriers. These include facilitating open dialog, supporting and advancing research, advocacy at various forums and contributing to the development of standards and guidelines.

• USP

• API
• OSD

1. 3D printing
2. environmental impact
3. Loss-in-weight feeder
4. real-time release testing (RTRT)
5. Sustainability